Histone demethylase JMJD1A promotes colorectal cancer growth and metastasis by enhancing Wnt/β-catenin signaling

The histone demethylase Jumonji domain containing 1A (JMJD1A) is overexpressed in multiple tumors and promotes cancer progression. JMJD1A has been shown to promote colorectal cancer (CRC) progression, but its molecular role in CRC is unclear. Here, we report that JMJD1A is overexpressed in CRC speci...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Peng, Kesong, Su, Guoqiang, Ji, Jinmeng, Yang, Xiaojia, Miao, Mengmeng, Mo, Pingli, Li, Ming, Xu, Jianming, Li, Wengang, Yu, Chundong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036217/
https://ncbi.nlm.nih.gov/pubmed/29802196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001730
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