Histone demethylase JMJD1A promotes colorectal cancer growth and metastasis by enhancing Wnt/β-catenin signaling

The histone demethylase Jumonji domain containing 1A (JMJD1A) is overexpressed in multiple tumors and promotes cancer progression. JMJD1A has been shown to promote colorectal cancer (CRC) progression, but its molecular role in CRC is unclear. Here, we report that JMJD1A is overexpressed in CRC speci...

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Publicado en:J Biol Chem
Autores principales: Peng, Kesong, Su, Guoqiang, Ji, Jinmeng, Yang, Xiaojia, Miao, Mengmeng, Mo, Pingli, Li, Ming, Xu, Jianming, Li, Wengang, Yu, Chundong
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036217/
https://ncbi.nlm.nih.gov/pubmed/29802196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001730
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