Demethylase-independent function of JMJD2D as a novel antagonist of p53 to promote Liver Cancer initiation and progression

Background: As a histone demethylase, JMJD2D can enhance gene expression by specifically demethylating H3K9me2/3 and plays an important role in promoting colorectal cancer progression. However, its role in liver cancer remains unclear. Methods: The expression of JMJD2D was examined in human liver ca...

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Veröffentlicht in:Theranostics
Hauptverfasser: Li, Ming, Deng, Yuan, Zhuo, Minghui, Zhou, Hui, Kong, Xu, Xia, Xiaogang, Su, Zhaojie, Chen, Qiang, Guo, Peng, Mo, Pingli, Yu, Chundong, Li, Wengang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7392006/
https://ncbi.nlm.nih.gov/pubmed/32754284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.45581
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