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Jmjd3 Negatively Regulates Reprogramming Through Histone Demethylase Activity- Dependent and -Independent Pathways
Although somatic cell reprogramming to generate inducible pluripotent stem cells (iPSCs) is associated with profound epigenetic changes, the roles and mechanisms of epigenetic factors in this process remain poorly understood. Here we identify Jmjd3 as a potent negative regulator of reprogramming. Jm...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3742052/ https://ncbi.nlm.nih.gov/pubmed/23452852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.02.006 |
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