Critical role of histone demethylase Jmjd3 in the regulation of CD4(+) T cell differentiation

Epigenetic factors have been implicated in the regulation of CD4(+) T cell differentiation. Jmjd3 plays a role in many biological processes, but its in vivo function in T cell differentiation remains unknown. Here, we report that Jmjd3 ablation promotes CD4(+) T cell differentiation into Th2 and Th1...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Li, Qingtian, Zou, Jia, Wang, Mingjun, Ding, Xilai, Chepelev, Iouri, Zhou, Xikun, Zhao, Wei, Wei, Gang, Cui, Jun, Zhao, Keji, Wang, Helen Y., Wang, Rong-Fu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274750/
https://ncbi.nlm.nih.gov/pubmed/25531312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6780
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