Modulators of histone demethylase JMJD1C selectively target leukemic stem cells

Leukemic stem cells (LSCs) comprise a very rare cell population that results in the development of acute myeloid leukemia. The selective targeting of drivers in LSCs with small molecule inhibitors holds promise for treatment of acute myeloid leukemia. Recently, we reported the identification of inhi...

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Dades bibliogràfiques
Publicat a:FEBS Open Bio
Autors principals: Yang, Yong, Zhang, Xinjing, Zhang, Xiaoyan, Wang, Yishu, Wang, Xintong, Hu, Linda, Zhao, Yao, Wang, Haihua, Wang, Zhanju, Wang, Haiying, Wang, Lin, Dirks, Wilhelm G., Drexler, Hans G., Xu, Xin, Hu, Zhenbo
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780120/
https://ncbi.nlm.nih.gov/pubmed/33289299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.13054
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