Modulators of histone demethylase JMJD1C selectively target leukemic stem cells

Leukemic stem cells (LSCs) comprise a very rare cell population that results in the development of acute myeloid leukemia. The selective targeting of drivers in LSCs with small molecule inhibitors holds promise for treatment of acute myeloid leukemia. Recently, we reported the identification of inhi...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Yang, Yong, Zhang, Xinjing, Zhang, Xiaoyan, Wang, Yishu, Wang, Xintong, Hu, Linda, Zhao, Yao, Wang, Haihua, Wang, Zhanju, Wang, Haiying, Wang, Lin, Dirks, Wilhelm G., Drexler, Hans G., Xu, Xin, Hu, Zhenbo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780120/
https://ncbi.nlm.nih.gov/pubmed/33289299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.13054
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