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Aptamers as Therapeutics
Aptamers are single-stranded nucleic acid molecules that bind to and inhibit proteins and are commonly produced by systematic evolution of ligands by exponential enrichment (SELEX). Aptamers undergo extensive pharmacological revision, which alters affinity, specificity, and therapeutic half-life, ta...
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| Publicado no: | Annu Rev Pharmacol Toxicol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6035745/ https://ncbi.nlm.nih.gov/pubmed/28061688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010716-104558 |
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