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Therapeutic Aptamers: Evolving to Find their Clinical Niche
BACKGROUND: The discovery that short oligonucleotides, termed aptamers, can fold into three-dimensional structures that allow them to selectively bind and inhibit the activity of pathogenic proteins is now over 25 years old. The invention of the SELEX methodology heralded in an era in which such nuc...
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| Publicado no: | Curr Med Chem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8177732/ https://ncbi.nlm.nih.gov/pubmed/31573879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/0929867326666191001125101 |
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