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Inhibition of Glycogen Synthase II with RNAi Prevents Liver Injury in Mouse Models of Glycogen Storage Diseases

Glycogen storage diseases (GSDs) of the liver are devastating disorders presenting with fasting hypoglycemia as well as hepatic glycogen and lipid accumulation, which could lead to long-term liver damage. Diet control is frequently utilized to manage the potentially dangerous hypoglycemia, but there...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Ther
Auteurs principaux: Pursell, Natalie, Gierut, Jessica, Zhou, Wei, Dills, Michael, Diwanji, Rohan, Gjorgjieva, Monika, Saxena, Utsav, Yang, Jr-Shiuan, Shah, Anee, Venkat, Nandini, Storr, Rachel, Kim, Boyoung, Wang, Weimin, Abrams, Marc, Raffin, Margaux, Mithieux, Gilles, Rajas, Fabienne, Dudek, Henryk, Brown, Bob D., Lai, Chengjung
Format: Artigo
Langue:Inglês
Publié: American Society of Gene & Cell Therapy 2018
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035741/
https://ncbi.nlm.nih.gov/pubmed/29784585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.04.023
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