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Lessons from new mouse models of glycogen storage disease type 1a in relation to the time course and organ specificity of the disease

Patients with glycogen storage diseases type 1 (GSD1) suffer from life-threatening hypoglycaemia, when left untreated. Despite an intensive dietary treatment, patients develop severe complications, such as liver tumors and renal failure, with aging. Until now, the animal models available for studyin...

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Bibliografische gegevens
Gepubliceerd in:J Inherit Metab Dis
Hoofdauteurs: Rajas, Fabienne, clar, julie, Gautier-Stein, Amandine, Mithieux, Gilles
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Kluwer 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522669/
https://ncbi.nlm.nih.gov/pubmed/25164786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10545-014-9761-0
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