Direct Inhibition of β-catenin: A new strategy for colorectal cancer

por Ganesh, Shanthi, Brown, Bob D., Abrams, Marc
Publicado en Oncoscience (2019)

Hepatic Lactate Dehydrogenase A: An RNA Interference Target for the Treatment of All Known Types of Primary Hyperoxaluria

por Ariceta, Gema, Barrios, Kelly, Brown, Bob D., Hoppe, Bernd, Rosskamp, Ralf, Langman, Craig B.
Publicado en Kidney Int Rep (2021)

RNAi-Mediated β-Catenin Inhibition Promotes T Cell Infiltration and Antitumor Activity in Combination with Immune Checkpoint Blockade

por Ganesh, Shanthi, Shui, Xue, Craig, Kevin P., Park, Jihye, Wang, Weimin, Brown, Bob D., Abrams, Marc T.
Publicado en Mol Ther (2018)

Glutathione and Bcl-2 targeting facilitates elimination by chemoradiotherapy of human A375 melanoma xenografts overexpressing bcl-xl, bcl-2, and mcl-1

por Mena, Salvador, Rodriguez, María L, Ortega, Angel, Priego, Sonia, Obrador, Elena, Asensi, Miguel, Petschen, Ignacio, Cerdá, Miguel, Brown, Bob D, Estrela, José M
Publicado 2012

β-catenin mRNA silencing and MEK inhibition display synergistic efficacy in preclinical tumor models

por Ganesh, Shanthi, Shui, Xue, Craig, Kevin P., Koser, Martin L., Chopda, Girish R., Cyr, Wendy A., Lai, Chengjung, Dudek, Henryk, Wang, Weimin, Brown, Bob D., Abrams, Marc T.
Publicado en Mol Cancer Ther (2017)

Direct pharmacological inhibition of β-catenin by RNA interference in tumors of diverse origin

por Ganesh, Shanthi, Koser, Martin, Cyr, Wendy, Chopda, Girish, Tao, Junyan, Shui, Xue, Ying, Bo, Chen, Dongyu, Pandya, Purva, Chipumuro, Edmond, Siddiquee, Zakir, Craig, Kevin, Lai, Chengjung, Dudek, Henryk, Monga, Satdarshan, Wang, Weimin, Brown, Bob D., Abrams, Marc
Publicado en Mol Cancer Ther (2016)

Inhibition of Glycogen Synthase II with RNAi Prevents Liver Injury in Mouse Models of Glycogen Storage Diseases

por Pursell, Natalie, Gierut, Jessica, Zhou, Wei, Dills, Michael, Diwanji, Rohan, Gjorgjieva, Monika, Saxena, Utsav, Yang, Jr-Shiuan, Shah, Anee, Venkat, Nandini, Storr, Rachel, Kim, Boyoung, Wang, Weimin, Abrams, Marc, Raffin, Margaux, Mithieux, Gilles, Rajas, Fabienne, Dudek, Henryk, Brown, Bob D., Lai, Chengjung
Publicado en Mol Ther (2018)

Knockdown of β-catenin with Dicer-Substrate siRNAs Reduces Liver Tumor Burden In vivo

por Dudek, Henryk, Wong, Darren H, Arvan, Rokhand, Shah, Anee, Wortham, Kathleen, Ying, Bo, Diwanji, Rohan, Zhou, Wei, Holmes, Benjamin, Yang, Hailin, Cyr, Wendy A, Zhou, Yi, Shah, Aalok, Farkiwala, Ruchir, Lee, Michael, Li, Yiting, Rettig, Garrett R, Collingwood, Michael A, Basu, Sujit K, Behlke, Mark A, Brown, Bob D
Publicado 2014

Inhibition of Glycolate Oxidase With Dicer-substrate siRNA Reduces Calcium Oxalate Deposition in a Mouse Model of Primary Hyperoxaluria Type 1

por Dutta, Chaitali, Avitahl-Curtis, Nicole, Pursell, Natalie, Larsson Cohen, Marita, Holmes, Benjamin, Diwanji, Rohan, Zhou, Wei, Apponi, Luciano, Koser, Martin, Ying, Bo, Chen, Dongyu, Shui, Xue, Saxena, Utsav, Cyr, Wendy A, Shah, Anee, Nazef, Naim, Wang, Weimin, Abrams, Marc, Dudek, Henryk, Salido, Eduardo, Brown, Bob D, Lai, Chengjung
Publicado en Mol Ther (2016)