Differentiation Therapy by Epigenetic Reconditioning Exerts Antitumor Effects on Liver Cancer Cells

Primary liver tumors are mainly represented by hepatocellular carcinoma (HCC), one of the most aggressive and resistant forms of cancer. Liver tumorigenesis is characterized by an accumulation of epigenetic abnormalities, leading to gene extinction and loss of hepatocyte differentiation. The aim of...

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Publicat a:Mol Ther
Autors principals: Gailhouste, Luc, Liew, Lee Chuen, Yasukawa, Ken, Hatada, Izuho, Tanaka, Yasuhito, Nakagama, Hitoshi, Ochiya, Takahiro
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2018
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035736/
https://ncbi.nlm.nih.gov/pubmed/29759938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.04.018
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