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Geometric compensation applied to image analysis of cell populations with morphological variability: a new role for a classical concept

Immunofluorescence is the gold standard technique to determine the level and spatial distribution of fluorescent-tagged molecules. However, quantitative analysis of fluorescence microscopy images faces crucial challenges such as morphologic variability within cells. In this work, we developed an ana...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Figueiredo, Joana, Rodrigues, Isabel, Ribeiro, João, Fernandes, Maria Sofia, Melo, Soraia, Sousa, Bárbara, Paredes, Joana, Seruca, Raquel, Sanches, João M.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035232/
https://ncbi.nlm.nih.gov/pubmed/29980764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28570-z
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