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Cigarette smoke extract enhances neutrophil elastase-induced IL-8 production via proteinase-activated receptor-2 upregulation in human bronchial epithelial cells

Although inflammation, oxidative stress, and protease-antiprotease imbalance have been referred to as a pathogenic triad in chronic obstructive pulmonary disease (COPD), little is known about how they interact. The objectives of this study were to elucidate the effect of cigarette smoke extract (CSE...

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Vydáno v:Exp Mol Med
Hlavní autoři: Lee, Kyoung-Hee, Lee, Jinwoo, Jeong, Jiyeong, Woo, Jisu, Lee, Chang-Hoon, Yoo, Chul-Gyu
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035212/
https://ncbi.nlm.nih.gov/pubmed/29980681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0114-1
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