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Neutrophil Elastase Differentially Regulates Interleukin 8 (IL-8) and Vascular Endothelial Growth Factor (VEGF) Production by Cigarette Smoke Extract

Inflammation by IL-8-induced neutrophil recruitment and apoptosis of epithelial cells by decreased expression of VEGF have been suggested as one of the complicated pathogenic mechanisms of chronic obstructive pulmonary disease (COPD). The role of neutrophil elastase (NE) in the development of COPD i...

詳細記述

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書誌詳細
出版年:J Biol Chem
主要な著者: Lee, Kyoung-Hee, Lee, Chang-Hoon, Jeong, Jiyeong, Jang, An-Hee, Yoo, Chul-Gyu
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653700/
https://ncbi.nlm.nih.gov/pubmed/26453303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.663567
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