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Neutrophil Elastase Differentially Regulates Interleukin 8 (IL-8) and Vascular Endothelial Growth Factor (VEGF) Production by Cigarette Smoke Extract

Inflammation by IL-8-induced neutrophil recruitment and apoptosis of epithelial cells by decreased expression of VEGF have been suggested as one of the complicated pathogenic mechanisms of chronic obstructive pulmonary disease (COPD). The role of neutrophil elastase (NE) in the development of COPD i...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Lee, Kyoung-Hee, Lee, Chang-Hoon, Jeong, Jiyeong, Jang, An-Hee, Yoo, Chul-Gyu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653700/
https://ncbi.nlm.nih.gov/pubmed/26453303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.663567
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