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Neutrophil Elastase Differentially Regulates Interleukin 8 (IL-8) and Vascular Endothelial Growth Factor (VEGF) Production by Cigarette Smoke Extract

Inflammation by IL-8-induced neutrophil recruitment and apoptosis of epithelial cells by decreased expression of VEGF have been suggested as one of the complicated pathogenic mechanisms of chronic obstructive pulmonary disease (COPD). The role of neutrophil elastase (NE) in the development of COPD i...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Lee, Kyoung-Hee, Lee, Chang-Hoon, Jeong, Jiyeong, Jang, An-Hee, Yoo, Chul-Gyu
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653700/
https://ncbi.nlm.nih.gov/pubmed/26453303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.663567
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