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Co-treatment of TGF-β3 and BMP7 is superior in stimulating chondrocyte redifferentiation in both hypoxia and normoxia compared to single treatments

Signaling by members of the transforming growth factor-β (TGF-β) superfamily, such as TGF-β3 and BMP7, and oxygen tension play a pivotal role in chondrocyte biology. The objective of this research was to investigate the endogenous BMP7 expression in human osteoarthritis (OA) cartilage and the effect...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Huang, Xiaobin, Zhong, Leilei, Post, Janine N., Karperien, Marcel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035177/
https://ncbi.nlm.nih.gov/pubmed/29980690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27602-y
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