The presence of large focal lesions is a strong independent prognostic factor in multiple myeloma

Spatial intratumor heterogeneity is frequently seen in multiple myeloma (MM) and poses a significant challenge for risk classifiers, which rely on tumor samples from the iliac crest. Because biopsy-based assessment of multiple skeletal sites is difficult, alternative strategies for risk stratificati...

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Pubblicato in:Blood
Autori principali: Rasche, Leo, Angtuaco, Edgardo J., Alpe, Terri L., Gershner, Grant H., McDonald, James E., Samant, Rohan S., Kumar, Manoj, Van Hemert, Rudy, Epstein, Joshua, Deshpande, Shayu, Tytarenko, Ruslana, Yaccoby, Shmuel, Hillengass, Jens, Thanendrarajan, Sharmilan, Schinke, Carolina, van Rhee, Frits, Zangari, Maurizio, Walker, Brian A., Barlogie, Bart, Morgan, Gareth J., Davies, Faith E., Weinhold, Niels
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2018
Soggetti:
Lymphoid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034645/
https://ncbi.nlm.nih.gov/pubmed/29784643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-04-842880
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