Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis

Microvesicles (MVs) are emerging as a new mechanism of intercellular communication by transferring cellular lipid and protein components to target cells, yet their function in disease is only now being explored. We found that neutrophil-derived MVs were increased in concentration in synovial fluid f...

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Veröffentlicht in:Sci Transl Med
Hauptverfasser: Headland, Sarah E., Jones, Hefin R., Norling, Lucy V., Kim, Andrew, Souza, Patricia R., Corsiero, Elisa, Gil, Cristiane D., Nerviani, Alessandra, Dell’Accio, Francesco, Pitzalis, Costantino, Oliani, Sonia M., Jan, Lily Y., Perretti, Mauro
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034622/
https://ncbi.nlm.nih.gov/pubmed/26606969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aac5608
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