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Introduction of F446I mutation in the K13 propeller gene leads to increased ring survival rates in Plasmodium falciparum isolates

BACKGROUND: Mutations in the Plasmodium falciparum k13 gene are associated with artemisinin (ART) resistance. However, it is unclear whether the F446I mutation, the most prevalent allele at the China–Myanmar border and north of Myanmar, is associated with ART resistance. Therefore, the aim of this s...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Wang, Jing, Huang, Yufu, Zhao, Yuemeng, Ye, Run, Zhang, Dongmei, Pan, Weiqing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034266/
https://ncbi.nlm.nih.gov/pubmed/29976207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-018-2396-0
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