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Secretagogin protects Pdx1 from proteasomal degradation to control a transcriptional program required for β cell specification
OBJECTIVE: Specification of endocrine cell lineages in the developing pancreas relies on extrinsic signals from non-pancreatic tissues, which initiate a cell-autonomous sequence of transcription factor activation and repression switches. The steps in this pathway share reliance on activity-dependent...
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| Publicado no: | Mol Metab |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6034064/ https://ncbi.nlm.nih.gov/pubmed/29910119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.05.019 |
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