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The small molecule drug diminazene aceturate inhibits liver injury and biliary fibrosis in mice

There is no established medical therapy to treat biliary fibrosis resulting from chronic inflammation in the biliary tree. We have recently shown that liver-specific over-expression of angiotensin converting enzyme 2 (ACE2) of the renin angiotensin system (RAS) ameliorated liver fibrosis in mice. Di...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Rajapaksha, Indu G., Mak, Kai Y., Huang, Ping, Burrell, Louise M., Angus, Peter W., Herath, Chandana B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033899/
https://ncbi.nlm.nih.gov/pubmed/29977014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28490-y
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