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The small molecule drug diminazene aceturate inhibits liver injury and biliary fibrosis in mice
There is no established medical therapy to treat biliary fibrosis resulting from chronic inflammation in the biliary tree. We have recently shown that liver-specific over-expression of angiotensin converting enzyme 2 (ACE2) of the renin angiotensin system (RAS) ameliorated liver fibrosis in mice. Di...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6033899/ https://ncbi.nlm.nih.gov/pubmed/29977014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28490-y |
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