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Hepatic stellate cell-derived PDGFRα-enriched extracellular vesicles promote liver fibrosis in mice through SHP2

Liver fibrosis is characterized by the activation and migration of hepatic stellate cells (HSCs) followed by matrix deposition. Recently, several studies have shown the importance of extracellular vesicles (EVs) derived from liver cells, such as hepatocytes and endothelial cells, in liver pathobiolo...

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Bibliografiske detaljer
Udgivet i:Hepatology
Main Authors: Kostallari, Enis, Hirsova, Petra, Prasnicka, Alena, Verma, Vikas K., Yaqoob, Usman, Wongjarupong, Nicha, Roberts, Lewis R., Shah, Vijay H.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033667/
https://ncbi.nlm.nih.gov/pubmed/29360139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29803
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