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Hepatic stellate cell autophagy inhibits extracellular vesicle release to attenuate liver fibrosis
BACKGROUND AND AIM: In chronic liver injury, platelet-derived growth factor (PDGF)-stimulated hepatic stellate cells (HSCs) release fibrogenic extracellular vesicles (EVs). EVs include multivesicular body (MVB)-derived exosomes and Rho-associated kinase (ROCK)-dependent plasma membrane budding-deriv...
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| Publicado no: | J Hepatol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7572579/ https://ncbi.nlm.nih.gov/pubmed/32389810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2020.04.044 |
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