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Role of drug transporters in the sensitivity of acute myeloid leukemia to sorafenib

BACKGROUND: Chemoresistance often limits the success of the pharmacological treatment in acute myeloid leukemia (AML) patients. Although positive results have been obtained with tyrosine kinase inhibitors (TKIs), such as sorafenib, especially in patients with Fms-like tyrosine kinase 3 (FLT3)-positi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Macias, Rocio I.R., Sánchez-Martín, Anabel, Rodríguez-Macías, Gabriela, Sánchez-Abarca, Luis I., Lozano, Elisa, Herraez, Elisa, Odero, Maria D., Díez-Martín, José L., Marin, Jose J.G., Briz, Oscar
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033373/
https://ncbi.nlm.nih.gov/pubmed/29983874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25494
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