Role of drug transporters in the sensitivity of acute myeloid leukemia to sorafenib

BACKGROUND: Chemoresistance often limits the success of the pharmacological treatment in acute myeloid leukemia (AML) patients. Although positive results have been obtained with tyrosine kinase inhibitors (TKIs), such as sorafenib, especially in patients with Fms-like tyrosine kinase 3 (FLT3)-positi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Macias, Rocio I.R., Sánchez-Martín, Anabel, Rodríguez-Macías, Gabriela, Sánchez-Abarca, Luis I., Lozano, Elisa, Herraez, Elisa, Odero, Maria D., Díez-Martín, José L., Marin, Jose J.G., Briz, Oscar
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033373/
https://ncbi.nlm.nih.gov/pubmed/29983874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25494
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