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Usefulness of the MRP2 promoter to overcome the chemoresistance of gastrointestinal and liver tumors by enhancing the expression of the drug transporter OATP1B1

Tumor response to chemotherapy is often limited by drug export through ABC proteins. To overcome this problem, here we have investigated the usefulness of inducing the expression of the multidrug uptake transporter OATP1B1 under the control of the MRP2 promoter (MRP2pr). Human hepatoma cells (Alexan...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Herraez, Elisa, Sanchez-Vicente, Laura, Macias, Rocio I.R., Briz, Oscar, Jose, J.G. Marin
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470996/
https://ncbi.nlm.nih.gov/pubmed/28423714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16119
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