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Mutations of p53 decrease sensitivity to the anthracycline treatments in bladder cancer cells
Due to doxorubicin (Dox) cardiotoxicity, the next generation of novel non-cardiotoxic anthracyclines, including AD 312 and AD 198, were synthesized and validated. In this study, we assessed the efficacy and mechanisms of anthracyclines-induced apoptosis and inhibition of cell viability in human blad...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6033348/ https://ncbi.nlm.nih.gov/pubmed/29983877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25530 |
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