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Inhibition of the PI3K/AKT Pathway Sensitizes Oral Squamous Cell Carcinoma Cells to Anthracycline-Based Chemotherapy In Vitro

Anthracycline-based chemotherapy, such as doxorubicin (Dox), while effective against many solid tumors, is not widely used for head and neck cancers. In this study, we evaluated the efficacy of Dox, and its derivative AD198 in human, canine, and feline oral squamous cell carcinomas cells (OSCC) in v...

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Detalhes bibliográficos
Publicado no:J Cell Biochem
Main Authors: Smolensky, Dmitriy, Rathore, Kusum, Bourn, Jennifer, Cekanova, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572634/
https://ncbi.nlm.nih.gov/pubmed/27649518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25747
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