p53 mutations in urinary bladder cancer

We have screened for mutations in exons 5–8 of the p53 gene in a series consisting of 189 patients with urinary bladder neoplasms. 82 (44%) neoplasms were lowly malignant (Ta, G1–G2a) and 106 (56%) were highly malignant (G2b–G4 or ≥T1). Only one mutation was in a lowly malignant urinary bladder neop...

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Detalhes bibliográficos
Main Authors: Berggren, P, Steineck, G, Adolfsson, J, Hansson, J, Jansson, O, Larsson, P, Sandstedt, B, Wijkström, H, Hemminki, K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363660/
https://ncbi.nlm.nih.gov/pubmed/11384101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1823
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