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Loss of heterozygosity is related to p53 mutations and smoking in lung cancer
Carcinogenesis results from an accumulation of several genetic alterations. Mutations in the p53 gene are frequent and occur at an early stage of lung carcinogenesis. Loss of multiple chromosomal regions is another genetic alteration frequently found in lung tumours. We have examined the association...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2363705/ https://ncbi.nlm.nih.gov/pubmed/11161381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1528 |
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