Highly Selective Directed Iridium‐Catalyzed Hydrogen Isotope Exchange Reactions of Aliphatic Amides

For the first time, we describe highly selective homogeneous iridium‐catalyzed hydrogen isotope exchange (HIE) of unactivated C(sp(3)) centers in aliphatic amides. When using the commercially available Kerr catalyst, the HIE with a series of common antibody–drug conjugate (ADC) linker side chains pr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Valero, Mégane, Weck, Remo, Güssregen, Stefan, Atzrodt, Jens, Derdau, Volker
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033151/
https://ncbi.nlm.nih.gov/pubmed/29693316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201804010
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados