An Artificial Heme Enzyme for Cyclopropanation Reactions

An artificial heme enzyme was created through self‐assembly from hemin and the lactococcal multidrug resistance regulator (LmrR). The crystal structure shows the heme bound inside the hydrophobic pore of the protein, where it appears inaccessible for substrates. However, good catalytic activity and...

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Dades bibliogràfiques
Publicat a:Angew Chem Int Ed Engl
Autors principals: Villarino, Lara, Splan, Kathryn E., Reddem, Eswar, Alonso‐Cotchico, Lur, Gutiérrez de Souza, Cora, Lledós, Agustí, Maréchal, Jean‐Didier, Thunnissen, Andy‐Mark W. H., Roelfes, Gerard
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033091/
https://ncbi.nlm.nih.gov/pubmed/29719099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201802946
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