Ibrutinib for chronic graft-versus-host disease after failure of prior therapy

Chronic graft-versus-host disease (cGVHD) is a serious complication of allogeneic stem cell transplantation with few effective options available after failure of corticosteroids. B and T cells play a role in the pathophysiology of cGVHD. Ibrutinib inhibits Bruton tyrosine kinase in B cells and inter...

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Enregistré dans:
Détails bibliographiques
Publié dans:Blood
Auteurs principaux: Miklos, David, Cutler, Corey S., Arora, Mukta, Waller, Edmund K., Jagasia, Madan, Pusic, Iskra, Flowers, Mary E., Logan, Aaron C., Nakamura, Ryotaro, Blazar, Bruce R., Li, Yunfeng, Chang, Stephen, Lal, Indu, Dubovsky, Jason, James, Danelle F., Styles, Lori, Jaglowski, Samantha
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2017
Sujets:
Plenary Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033048/
https://ncbi.nlm.nih.gov/pubmed/28924018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-07-793786
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