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Ibrutinib for chronic graft-versus-host disease after failure of prior therapy

Chronic graft-versus-host disease (cGVHD) is a serious complication of allogeneic stem cell transplantation with few effective options available after failure of corticosteroids. B and T cells play a role in the pathophysiology of cGVHD. Ibrutinib inhibits Bruton tyrosine kinase in B cells and inter...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Blood
Päätekijät: Miklos, David, Cutler, Corey S., Arora, Mukta, Waller, Edmund K., Jagasia, Madan, Pusic, Iskra, Flowers, Mary E., Logan, Aaron C., Nakamura, Ryotaro, Blazar, Bruce R., Li, Yunfeng, Chang, Stephen, Lal, Indu, Dubovsky, Jason, James, Danelle F., Styles, Lori, Jaglowski, Samantha
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033048/
https://ncbi.nlm.nih.gov/pubmed/28924018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-07-793786
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