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Ibrutinib for chronic graft-versus-host disease after failure of prior therapy
Chronic graft-versus-host disease (cGVHD) is a serious complication of allogeneic stem cell transplantation with few effective options available after failure of corticosteroids. B and T cells play a role in the pathophysiology of cGVHD. Ibrutinib inhibits Bruton tyrosine kinase in B cells and inter...
Tallennettuna:
Julkaisussa: | Blood |
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Päätekijät: | , , , , , , , , , , , , , , , , |
Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
American Society of Hematology
2017
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6033048/ https://ncbi.nlm.nih.gov/pubmed/28924018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-07-793786 |
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