Ibrutinib for chronic graft-versus-host disease after failure of prior therapy

Chronic graft-versus-host disease (cGVHD) is a serious complication of allogeneic stem cell transplantation with few effective options available after failure of corticosteroids. B and T cells play a role in the pathophysiology of cGVHD. Ibrutinib inhibits Bruton tyrosine kinase in B cells and inter...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Miklos, David, Cutler, Corey S., Arora, Mukta, Waller, Edmund K., Jagasia, Madan, Pusic, Iskra, Flowers, Mary E., Logan, Aaron C., Nakamura, Ryotaro, Blazar, Bruce R., Li, Yunfeng, Chang, Stephen, Lal, Indu, Dubovsky, Jason, James, Danelle F., Styles, Lori, Jaglowski, Samantha
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Plenary Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033048/
https://ncbi.nlm.nih.gov/pubmed/28924018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-07-793786
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