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Isolation of a high‐affinity Bet v 1‐specific IgG‐derived ScFv from a subject vaccinated with hypoallergenic Bet v 1 fragments

BACKGROUND: Recombinant hypoallergenic allergen derivatives have been used in clinical immunotherapy studies, and clinical efficacy seems to be related to the induction of blocking IgG antibodies recognizing the wild‐type allergens. However, so far no treatment‐induced IgG antibodies have been chara...

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Bibliografiska uppgifter
I publikationen:Allergy
Huvudupphovsmän: Gadermaier, E., Marth, K., Lupinek, C., Campana, R., Hofer, G., Blatt, K., Smiljkovic, D., Roder, U., Focke‐Tejkl, M., Vrtala, S., Keller, W., Valent, P., Valenta, R., Flicker, S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032869/
https://ncbi.nlm.nih.gov/pubmed/29315611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.13394
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