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Genetic engineering of trimers of hypoallergenic fragments of the major birch pollen allergen, Bet v 1, for allergy vaccination

An immunotherapy trial performed in allergic patients with hypoallergenic recombinant fragments, comprising aa 1–74 and 75–160 of the major birch pollen allergen, Bet v 1, has indicated that the induction of allergen-specific IgG responses may be an important mechanism of this treatment. To investig...

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Detalhes bibliográficos
Main Authors: Vrtala, Susanne, Fohr, Monika, Campana, Raffaela, Baumgartner, Christian, Valent, Peter, Valenta, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4092211/
https://ncbi.nlm.nih.gov/pubmed/21215346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.12.080
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