Altered IgE epitope presentation: A model for hypoallergenic activity revealed for Bet v 1 trimer

In order to reduce side effects in the course of allergen specific immunotherapy hypoallergenic allergen derivatives with reduced IgE reactivity have been made by genetic engineering. In contrast to other recombinant hypoallergenic allergen derivatives which showed reduced IgE reactivity, a recombin...

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Autori principali: Campana, Raffaela, Vrtala, Susanne, Maderegger, Bernhard, Dall’Antonia, Yuliya, Zafred, Domen, Blatt, Katharina, Herrman, Harald, Focke-Tejkl, Margarete, Swoboda, Ines, Scheiblhofer, Sandra, Gieras, Anna, Neubauer, Angela, Keller, Walter, Valent, Peter, Thalhamer, Josef, Spitzauer, Susanne, Valenta, Rudolf
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067515/
https://ncbi.nlm.nih.gov/pubmed/21093057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2010.09.016
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