Altered IgE epitope presentation: A model for hypoallergenic activity revealed for Bet v 1 trimer

In order to reduce side effects in the course of allergen specific immunotherapy hypoallergenic allergen derivatives with reduced IgE reactivity have been made by genetic engineering. In contrast to other recombinant hypoallergenic allergen derivatives which showed reduced IgE reactivity, a recombin...

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Autores principales: Campana, Raffaela, Vrtala, Susanne, Maderegger, Bernhard, Dall’Antonia, Yuliya, Zafred, Domen, Blatt, Katharina, Herrman, Harald, Focke-Tejkl, Margarete, Swoboda, Ines, Scheiblhofer, Sandra, Gieras, Anna, Neubauer, Angela, Keller, Walter, Valent, Peter, Thalhamer, Josef, Spitzauer, Susanne, Valenta, Rudolf
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067515/
https://ncbi.nlm.nih.gov/pubmed/21093057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2010.09.016
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