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Hypoallergenic derivatives of Fel d 1 obtained by rational reassembly for allergy vaccination and tolerance induction

BACKGROUND AND OBJECTIVE: The major cat allergen Fel d 1 represents one of the most important respiratory allergens. Aim of this study was to engineer recombinant Fel d 1 derivatives with reduced IgE reactivity and preserved T cell epitopes for vaccination and tolerance induction. METHODS: Seven rec...

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Detaylı Bibliyografya
Yayımlandı:Clin Exp Allergy
Asıl Yazarlar: Curin, M., Weber, M., Thalhamer, T., Swoboda, I., Focke-Tejkl, M., Blatt, K., Valent, P., Marth, K., Garmatiuk, T., Grönlund, H., Thalhamer, J., Spitzauer, S., Valenta, R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678659/
https://ncbi.nlm.nih.gov/pubmed/24552249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.12294
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