A hypoallergenic cat vaccine based on Fel d 1–derived peptides fused to hepatitis B PreS

BACKGROUND: Allergen-specific immunotherapy is clinically effective for the treatment of cat allergy but shows a high rate of side effects. OBJECTIVE: We sought to engineer recombinant fusion proteins for cat immunotherapy that allow reducing both IgE-mediated and T cell–mediated side effects. METHO...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Niespodziana, Katarzyna, Focke-Tejkl, Margarete, Linhart, Birgit, Civaj, Vera, Blatt, Katharina, Valent, Peter, van Hage, Marianne, Grönlund, Hans, Valenta, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624143/
https://ncbi.nlm.nih.gov/pubmed/21411130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.02.004
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