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A peptide‐display protein scaffold to facilitate single molecule force studies of aggregation‐prone peptides

Protein aggregation is linked with the onset of several neurodegenerative disorders, including Parkinson's disease (PD), which is associated with the aggregation of α‐synuclein (αSyn). The structural mechanistic details of protein aggregation, including the nature of the earliest protein–protei...

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Vydáno v:Protein Sci
Hlavní autoři: Doherty, Ciaran P. A., Young, Lydia M., Karamanos, Theodoros K., Smith, Hugh I., Jackson, Matthew P., Radford, Sheena E., Brockwell, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032367/
https://ncbi.nlm.nih.gov/pubmed/29417650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3386
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