MK-0677, a Ghrelin Agonist, Alleviates Amyloid Beta-Related Pathology in 5XFAD Mice, an Animal Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive deficits, neuroinflammation, and neuronal death. The primary pathogenic cause is believed to be the accumulation of pathogenic amyloid beta (Aβ) assemblies in the brain. Ghrelin, which is a peptide hormon...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Jeong, Yu-on, Shin, Soo Jung, Park, Jun Yong, Ku, Bo Kyeong, Song, Ji Soo, Kim, Jwa-Jin, Jeon, Seong Gak, Lee, Sang Min, Moon, Minho
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032329/
https://ncbi.nlm.nih.gov/pubmed/29912176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19061800
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