Intrahippocampal injection of a lentiviral vector expressing neurogranin enhances cognitive function in 5XFAD mice

Progressive cognitive declines are the main clinical symptoms of Alzheimer’s disease (AD). Cognitive impairment in AD is directly correlated with amyloid beta (Aβ)-mediated synaptic deficits. It is known that upregulation of neurogranin (Ng), a postsynaptic protein, contributes to the enhancement of...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Exp Mol Med
Main Authors: Jeon, Seong Gak, Kang, Moonkyung, Kim, Yeon-Soo, Kim, Dong-Hyun, Nam, Dong Woo, Song, Eun Ji, Mook-Jung, Inhee, Moon, Minho
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2018
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898899/
https://ncbi.nlm.nih.gov/pubmed/29568074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.302
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker