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Nurr1 (NR4A2) regulates Alzheimer’s disease‐related pathogenesis and cognitive function in the 5XFAD mouse model

The orphan nuclear receptor Nurr1 (also known as NR4A2) is critical for the development and maintenance of midbrain dopaminergic neurons, and is associated with Parkinson's disease. However, an association between Nurr1 and Alzheimer's disease (AD)‐related pathology has not previously been...

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Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: Moon, Minho, Jung, Eun Sun, Jeon, Seong Gak, Cha, Moon‐Yong, Jang, Yongwoo, Kim, Woori, Lopes, Claudia, Mook‐Jung, Inhee, Kim, Kwang‐Soo
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351845/
https://ncbi.nlm.nih.gov/pubmed/30515963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12866
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