Intrahippocampal injection of a lentiviral vector expressing neurogranin enhances cognitive function in 5XFAD mice

Progressive cognitive declines are the main clinical symptoms of Alzheimer’s disease (AD). Cognitive impairment in AD is directly correlated with amyloid beta (Aβ)-mediated synaptic deficits. It is known that upregulation of neurogranin (Ng), a postsynaptic protein, contributes to the enhancement of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Jeon, Seong Gak, Kang, Moonkyung, Kim, Yeon-Soo, Kim, Dong-Hyun, Nam, Dong Woo, Song, Eun Ji, Mook-Jung, Inhee, Moon, Minho
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898899/
https://ncbi.nlm.nih.gov/pubmed/29568074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.302
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados