MK-0677, a Ghrelin Agonist, Alleviates Amyloid Beta-Related Pathology in 5XFAD Mice, an Animal Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive deficits, neuroinflammation, and neuronal death. The primary pathogenic cause is believed to be the accumulation of pathogenic amyloid beta (Aβ) assemblies in the brain. Ghrelin, which is a peptide hormon...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Jeong, Yu-on, Shin, Soo Jung, Park, Jun Yong, Ku, Bo Kyeong, Song, Ji Soo, Kim, Jwa-Jin, Jeon, Seong Gak, Lee, Sang Min, Moon, Minho
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032329/
https://ncbi.nlm.nih.gov/pubmed/29912176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19061800
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