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Role of TLR4 signaling in the nephrotoxicity of heme and heme proteins
Destabilized heme proteins release heme, and free heme is toxic. Heme is now recognized as an agonist for the Toll-like receptor-4 (TLR4) receptor. This study examined whether the TLR4 receptor mediates the nephrotoxicity of heme, specifically, the effects of heme on renal blood flow and inflammator...
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| Опубликовано в: : | Am J Physiol Renal Physiol |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Physiological Society
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6031913/ https://ncbi.nlm.nih.gov/pubmed/28978536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00432.2017 |
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