Antithrombotic effects of heme-degrading and heme-binding proteins

In the murine venous thrombosis model induced by ligation of the inferior vena cava (IVCL), genetic deficiency of heme oxygenase-1 (HO-1) increases clot size. This study examined whether induction of HO-1 or administration of its products reduces thrombosis. Venous HO-1 upregulation by gene delivery...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Nath, Karl A., Grande, Joseph P., Belcher, John D., Garovic, Vesna D., Croatt, Anthony J., Hillestad, Matthew L., Barry, Michael A., Nath, Meryl C., Regan, Raymond F., Vercellotti, Gregory M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7099452/
https://ncbi.nlm.nih.gov/pubmed/32004074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00280.2019
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