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Identification of Novel Inhibitors for a Low Molecular Weight Protein Tyrosine Phosphatase via Virtual Screening

The human cytoplasmic protein tyrosine phosphatase (HCPTP) has been identified as a potential target for inhibition in order to downregulate metastatic transformation in several human epithelial cancers such as breast, prostate and colon cancer. Docking with two scoring functions on both isoforms of...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Homan, Kristoff T., Balasubramaniam, Deepa, Zabell, Adam P.R., Wiest, Olaf, Helquist, Paul, Stauffacher, Cynthia V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031871/
https://ncbi.nlm.nih.gov/pubmed/20538467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.04.050
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