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Molecular docking and virtual screening for novel protein tyrosine phosphatase 1B (PTP1B) inhibitors

Protein tyrosine phosphatase 1B (PTP1B) functions as major negative regulator of insulin and leptin signaling pathways. In view of this, PTP1B is an significant target for drug development against cancer, diabetes and obesity. The aim of the current study is to identify PTP1B inhibitors by means of...

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Detalhes bibliográficos
Main Authors: Rao, Pasupuleti Sreenivasa, Muvva, Charuvaka, Geethanjali, Karli, Bastipati, Suresh Babu, Kalashikam, Rajitha
Formato: Artigo
Idioma:Inglês
Publicado em: Biomedical Informatics 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488847/
https://ncbi.nlm.nih.gov/pubmed/23139594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630008834
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